New Biorxiv manuscript

Camilla’s preprint is out! “Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy by involving an Integrin-αVβ6/TGF-β Signaling Cascade” click
Together with our colleagues form Cardiology, Bioinformatics and Legal medicine we generated and characterized a novel mouse model of Arrhythmogenic cardiomyopathy (ACM) based on defective desmosomal adhesion. We used this model to identify a novel pathway for fibrosis generation in ACM hearts.