New paper out

Congratulations Jakob and Camilla for publishing the manuscript “The N Terminus of Adhesion G Protein–Coupled Receptor GPR126/ADGRG6 as Allosteric Force Integrator” ind Frontiers Cell and Developmental Biology! Link

Poster presentation award

Marie has just received the poster award at the 115. Annual Meeting of the german Anatomical Society for her poster “Combining AFM-based functional imaging with fluorescence reporters to outline adhesion-dependent signaling”. Congratulations Marie and thank you for presenting your work in such concise and convincing way!

New manuscript on BioRxiv

A new manuscript from our collaborator Ines Liebscher and us is out on BioRxiv: “Mimicking extracellular matrix-mediated mechano-activation by antibodies to control signaling of the adhesion G protein-coupled receptor GPR126/ADGRG6” click Jakob, a visiting student from the Liebscher lab, has set up a technique together with Camilla to modulate adhesion-GPCR signaling by AFM force spectroscopyContinue reading “New manuscript on BioRxiv”

New Biorxiv manuscript

Camilla’s preprint is out! “Defective Desmosomal Adhesion Causes Arrhythmogenic Cardiomyopathy by involving an Integrin-αVβ6/TGF-β Signaling Cascade” clickTogether with our colleagues form Cardiology, Bioinformatics and Legal medicine we generated and characterized a novel mouse model of Arrhythmogenic cardiomyopathy (ACM) based on defective desmosomal adhesion. We used this model to identify a novel pathway for fibrosis generationContinue reading “New Biorxiv manuscript”